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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN3 All Species: 16.36
Human Site: S93 Identified Species: 25.71
UniProt: Q6P5Z2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P5Z2 NP_037487.2 889 99421 S93 G P A E P V A S G P R P W A E
Chimpanzee Pan troglodytes XP_001159776 886 99121 S93 G P A E P V A S G P R P W A E
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 S206 D P A E P V A S G P R P W A E
Dog Lupus familis XP_548434 951 104664 P155 G Q A E P V A P G P Q P P A E
Cat Felis silvestris
Mouse Mus musculus Q8K045 878 97863 S86 A S A E P V T S E P Q P R A E
Rat Rattus norvegicus O08874 985 112050 S110 L N A H I V V S D P E D Y T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 P193 L P G P A V S P D P C R W E E
Chicken Gallus gallus XP_422357 1013 114806 T149 D V A D C P R T P D T P N S D
Frog Xenopus laevis Q7ZX15 486 56292
Zebra Danio Brachydanio rerio XP_697542 940 106140 P105 V M D D A T S P D P C H W E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 T58 K T Q V R P K T N E P R W N E
Sea Urchin Strong. purpuratus XP_787090 799 90414 L53 T S A V E L Q L T P I E F R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 F81 G S E D N E R F N S K E Y G F
Red Bread Mold Neurospora crassa P87253 1142 127954 L75 H G V D N M S L G A S P M S G
Conservation
Percent
Protein Identity: 100 97.7 81.5 84.2 N.A. 83.2 49.9 N.A. 64.2 48.9 26.2 52.2 N.A. 28 N.A. 29.1 41.5
Protein Similarity: 100 97.8 82.9 87.6 N.A. 88.4 63.6 N.A. 72.9 63 36.6 67.6 N.A. 41.5 N.A. 43.9 58.2
P-Site Identity: 100 100 93.3 73.3 N.A. 60 26.6 N.A. 33.3 13.3 0 20 N.A. 0 N.A. 13.3 13.3
P-Site Similarity: 100 100 93.3 80 N.A. 66.6 40 N.A. 40 40 0 33.3 N.A. 0 N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.2 27.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 43.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 54 0 14 0 27 0 0 7 0 0 0 34 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 14 0 0 0 0 % C
% Asp: 14 0 7 27 0 0 0 0 20 7 0 7 0 0 14 % D
% Glu: 0 0 7 34 7 7 0 0 7 7 7 14 0 14 54 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 7 % F
% Gly: 27 7 7 0 0 0 0 0 34 0 0 0 0 7 7 % G
% His: 7 0 0 7 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 7 0 0 0 7 0 0 0 0 % K
% Leu: 14 0 0 0 0 7 0 14 0 0 0 0 0 0 0 % L
% Met: 0 7 0 0 0 7 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 7 0 0 14 0 0 0 14 0 0 0 7 7 0 % N
% Pro: 0 27 0 7 34 14 0 20 7 60 7 47 7 0 0 % P
% Gln: 0 7 7 0 0 0 7 0 0 0 14 0 0 0 0 % Q
% Arg: 0 0 0 0 7 0 14 0 0 0 20 14 7 7 0 % R
% Ser: 0 20 0 0 0 0 20 34 0 7 7 0 0 14 0 % S
% Thr: 7 7 0 0 0 7 7 14 7 0 7 0 0 7 0 % T
% Val: 7 7 7 14 0 47 7 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _